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EDRS 2012
26
POSTER SESSION 1 ABSTRACTS
T2
NORMS AND DISCRIMINATIVE VALIDITY OF THE EATING
DISORDER EXAMINATION QUESTIONNAIRE (EDE-Q)
Jiska J. Aardoom, Alexandra E. Dingemans, Margarita C.
Slof-Op ‘t Landt, Eric F. van Furth
Center for Eating Disorders ‘Ursula’, Leidschendam, Nether-
lands
This study aimed to provide norms for the Eating Disorder Ex-
amination Questionnaire (EDE-Q) in a clinical sample of indi-
viduals with an eating disorder (ED), and a general population
sample without an ED. Norms for obese individuals without
an ED were provided as a more relevant comparison group
for individuals with binge eating disorder. The second aim
was to investigate the discriminative validity of the EDE-Q.
A sample of females with an ED (
N
= 935), women from
the general population without an ED (
N
= 235), and obese
females without an ED
(N
= 321) completed the EDE-Q.
Explorative factor analyses and receiver operating character-
istic analyses were conducted. The theorized four subscales
of the EDE-Q were not supported. Norms for EDE-Q global
scores were provided for each of the three samples. Within
the ED sample, norms were provided separately for patients
with different ED diagnoses. The EDE-Q global score was
highly accurate in discriminating individuals with an ED from
those without, and moderately accurate in discriminating
individuals with binge eating disorder from those with obesity.
The presented norms contribute to a more accurate interpre-
tation of EDE-Q scores, providing an index of the severity lev-
el of ED psychopathology. Furthermore, these norms can be
used to assess clinical significant change during treatment. In
addition, this study demonstrates that the EDE-Q, when using
its global score, is a valid instrument to assess levels of ED
psychopathology.
T3
Temperament and character in extreme weight condi-
tions
Zaida Agüera
1,2
, Carolina Sancho
1
, Isabel sánchez
1
, Susana
Jiménez-Murcia
1,2
, Laurence Claes
3
, Rita Castro
1
, Roser
Granero
2,4
, Salomé Tárrega
4
, Cristina Botella
2,5
, Rafael de
la Torre
2,6
, José M Fernández-Real
2,7
, Gemma Frühbeck
2,8
,
Francisco J Tinahones
2,9
, Maribel Covas
2,10
, Felipe F Casanu-
eva
2,11
, Fernando Fernández-Aranda
1,2
1
Department of Psychiatry, University Hospital of Bellvit-
ge, Barcelona, Spain,
2
CIBER Fisiología de la Obesidad y
Nutrición, Santiago de Compostela, Spain,
3
Department of
Psychology, Catholic University of Leuven, Lueven, Belgium,
4
Department of Psychobiology and Methodology of Health
Sciences, UAB, Barcelona, Spain,
5
Department of Basic
Psychology, Clinic and Psychobiology of the University Jau-
me I, Castellón, Spain,
6
Human Pharmacology and Clinical
Neurosciences Research Group, Institut Municipal d’Inves-
tigació Mèdica (IMIM-Hospital del Mar), Barcelona, Spain,
7
Service of Diabetes, Endocrinology and Nutrition, Institut
d’Investigació Biomèdica de Girona (IdIBGi) Hospital Dr
Josep Trueta, Girona, Spain,
8
Department of Endocrinology,
University of Navarra, Pamplona, Spain,
9
Service of Diabetes,
Endocrinology and Nutrition, Hospital Clínico Universitario
Virgen de Victoria, Málaga, Spain,
10
Cardiovascular Risk and
Nutrition and Human Pharmacology and Clinical Neurosci-
ences Research Groups, Institut Municipal d´Investigació
Mèdica (IMIM-Hospital del Mar), Barcelona, Spain,
11
Labora-
tory of Molecular and Cellular Endocrinology, Research Area,
Complejo Hospitalario Universitario de Santiago, Santiago de
Compostela, Spain
Introduction:
Research has largely suggested that temper-
ament and character could influence physical and mental
health. Different results from the studies that have dealt with
these issues specify that personality and BMI are related.
Based on this dimensions the main objective of this study
was, to assess in a broad range of BMI, the extent to which
personality traits are related to BMI.
Methods:
The TCI-R
was administered to 391 AN patients, 248 healthy controls
(26 underweight, 196 normal weight, 26 overweight) and 200
obese (50 obese and 150 morbid obese) subjects, with BMI
ranging from 11.22 to 60.08 (mean BMI: 24.70±11.47). All
the subjects were females and were diagnosed according
to DSM-IV criteria. Additional assessment measures includ-
ed the EDI-2, the SCL-90-R as well as a number of other
clinical and psychopathological indices.
Results:
Significant
differences were found in the scales of TCI-R (p<.01), except
for among the groups. Whereas anorexic patients were
characterized by the highest scores in Harm Avoidance and
Persistence (p<.0.01), and the lowest scores of Self-Direct-
edness (p<.05), the obese group showed the lowest Per-
sistence scores (p<.001) and the highest scores on Reward
Dependence and Cooperativeness (p<.002). Furthermore
it was found as predictors of BMI, Reward Dependence
(p<.05), Persistence (p<.05), and Self-Directedness (p<.001).
Conclusions:
Our findings suggest an association between
temperament (Reward Dependence and Persistence) and
character (Self-Directedness) with BMI.
T4
VARIATIONS OF SYMPTOMATOLOGY AND OBSES-
SIVENESS-RELATED TRAITS IN EATING DISORDERS
REFLECT UNDERLYING GENETIC VARIATIONS AT
THE 5-HTTLPR.
Kirsti Akkermann
1
, Anu Aluoja
2
, Marlen Herik
3
, Anu Järv
3
, Kelli
Hiio
1
, Jüri Parik
4
, Jaanus Harro
1
1
Institute of Psychology,Estonian Centre of Behavioural and
Health Sciences, University of Tartu, Tartu, Estonia,
2
Depart-
ment of Psychiatry, University of Tartu, Tartu, Estonia,
3
Eating
Disorders Centre, Psychiatry Clinic, Tartu University Hospital,
Tartu, Estonia,
4
Institute of Molecular and Cell Biology, Uni-
versity of Tartu, Tartu, Estonia
Objective. Anorexia nervosa patients are often described as
obsessive and perfectionistic as opposed to bulimia nervosa
patients who exhibit impulsive behaviour and emotional insta-
bility. However, the studies have shown that the division by
personality traits is not dependent on ED diagnosis. Rather
it has been suggested that genetic factors may explain trait
based variations which may have significant influence on the
course of the illness and treatment response. The aim of the
current study was to investigate whether allelic differences
in the serotonin transporter gene-linked polymorphic region
(5-HTTLPR) are associated with the obsessive traits in ED
patients. Methods. The study comprised altogether 143
women (90 ED patients and 53 age matched controls). The
diagnostic assessment was carried out according to DSM-
IV-TR diagnostic criteria. The blood samples and data about
eating behaviour and attitudes were collected during the
first days of hospitalization, and other psychological mea-
surements were completed following days. Results. Patients
homozygous for the 5-HTTLPR long allele exhibited higher
scores in preoccupation with body image and body weight
and concern over mistakes independent of the ED diagnosis.
Conclusions. Based on our results it could be speculated that
homozygosity for the 5-HTTLPR long allele reflects highly
preoccupied and rigid ED individuals possibly corresponding
to the constricted/compulsive ED subgroup.
POSTER SESSION 1 ABSTRACTS - THURSDAY