Basic HTML Version
EDRS 2012
50
F34
Piloting an Integrated Universal, Selected, and Indicat-
ed Eating Disorder Prevention Initiative at Two College
Campuses
Megan Jones
1
, Andrea E. Kass
2
, Varvara Mazina
1
, Aimee
Zhang
1
, Mickey Trockel
1
, Katherine Taylor Lynch
3
, Corinna
Jacobi
4
, Denise Wilfley
2
, C. Barr Taylor
1
1
Stanford University, Stanford, CA, USA,
2
Washington Uni-
versity, St. Louis, MO, USA,
3
PGSP-Stanford PsyD Consor-
tium, Palo Alto, CA, USA,
4
Technische Universität Dresden,
Dresden, Germany
Purpose.
Evidence-based ED prevention programs exist,
yet attempts to systematically integrate these programs for
defined populations are scant. The complementary Healthy
Body Image Program at Stanford University (SU) and Com-
munity Wellness Initiative at Washington University (WU)
provide a model of a universal screening and intervention
initiative, enacted via community and online resources for
college students. An efficient, online screening tool was used
to identify male and female students at varying levels of risk
or ED symptom status and direct them to targeted, online
interventions or further evaluation. Universal prevention
programs to improve community culture around nutrition and
body esteem were offered to all students.
Methods.
Pilot
testing is currently underway at the two sites.
Results.
At
present, 232 students at SU completed the screen, which
identified 100 at low risk for developing an ED, 96 at high risk,
and 36 probable ED cases. At WU, 240 students completed
the screen, which identified 192 at low risk; 44 at high risk,
and 4 probable cases. Outreach activities reached over 3,000
students and evaluations have yielded consistently positive
results.
Conclusions.
Results suggest the program is feasi-
ble, effective, and acceptable to students and administrators
and may provide an effective model for integrating universal,
selected, and indicated prevention and early intervention at
individual and social-culture levels in a defined population.
F35
IS IMPAIRED SET SHIFTING IN ADOLESCENTS WITH AN-
OREXIA NERVOSA ASSOCIATED WITH DEPRESSION?
Viola Kappel, Betteke van Noort, Ernst Pfeiffer, Ulrike Lehm-
kuhl
Charité-Universitätsmedizin Berlin, Department of Child and
Adolescent Psychiatry, Psychosomatics, and Psychotherapy,
Berlin, Germany
Introduction. Neuropsychological studies in adolescents and
adults with Anorexia nervosa (AN) reveal deficits in set-shift-
ing (Roberts et al., 2007; Stedal et al., 2012). It has been
suggested that these impairments play a crucial role in the
development and maintenance of AN (Bulik et al., 2007).
However, set-shifting impairments are also present in com-
mon comorbid disorders of AN, such as depression (Baune
et al., 2012). Therefore the question arises whether these
deficits are AN-specific or related to concurrent depression.
Methods. The Trail Making Test (Delis et al., 2001), and a
standardized German self-report questionnaire on depression
(DIKJ, Stiensmeier-Pelster et al., 2000) were administered to
30 adolescents with AN, and to 30 age matched healthy con-
trols (HC), as part of a wider, ongoing study of neuropsycho-
logical performance in adolescent AN. Results. Preliminary
analyses on a subsample show low set-shifting performance
in adolescents with AN compared to HC. Depression scores
in AN are significantly higher than in HC. Further analyses will
explore the association between set-shifting and depression
scores. Conclusions. This controlled study will reveal insight
in the association between set-shifting abilities and depres-
sion in adolescent AN. Further research is needed to better
understand the role of depression in cognitive functioning in
AN.
F36
Olanzapine in adolescents with anorexia nervosa: a pilot
study using therapeutic drug monitoring
Andreas FK Karwautz, Margarethe Moyses, Julia Huemer,
Sandra Mader, Clarissa Laczkovics, Helmut Krönke
Medical University Vienna, Vienna, Austria
Introduction:
Antipsychotics seem to positively influence
distorted thinking about body image and food intake in AN.
Olanzapine could have an effect on weight, agitation, and
mood. In pediatric populations, off–label use is common and
drugs should be given under controlled conditions includ-
ing serum levels, e.g. using Therapeutic Drug Monitoring.
Methods:
In our pilot, 16
adolescent females between the
ages of 11 and 17, diagnosed with AN/R, received multipro-
fessional treatment and olanzapine over a time course of
five weeks in addition. We started with 5mg/d and 10mg/d
for the remaining four weeks. Outcome and side effects
were captured with EDE-Interviews, EDI-2, Y-BOCS, CDRS,
PANSS, PAERS, and GAF.
Results:
On average, the serum
levels of olanzapine were 32,56ng/ml (range 0-69) in the first
assay (T1) and 36,19ng/ml (range 0-65) in the second one
(T2). Restrained eating behavior declined [T0: 20,38 (range
0-30), T2: 13,94 (range 0-30)], GAF-Score increased to 51,88
(range 31-75) within the five weeks [T0: 42,00 (range 5-68)].
BMI raised from 14,84 (range 12,06-17,82) to 16,67 (range
13,50 -19,98). The most common adverse event was tired-
and sleepiness.
Conclusion:
We conclude that olanzapine
can be valued as partially effective and low in side effects for
severly ill AN-inpatients. It may increase the patients’ compli-
ance and may lead to improvements concerning weight gain,
body dissatisfaction and delusional thinking. Larger studies
are required.
F37
The Role of Stakeholder Involvement in Dissemination
and Implementation Research: Piloting an Integrated Uni-
versal, Selected, and Indicated Eating Disorder Preven-
tion Initiative at Two College Campuses
Andrea E. Kass
1
, Megan Jones
2
, Alan I. Glass
1
, Connie
Diekman
1
, Jill Stratton
1
, Dorothy J. Van Buren
1
, Myra Altman
1
,
Varvara Mazina
2
, Mickey Trockel
2
, C. Barr Taylor
2
, Denise E.
Wilfley
1, 3
1
Washington University in St. Louis, St. Louis, MO, USA,
2
Stanford University, Palo Alto, CA, USA,
3
Washington Uni-
versity School of Medicine, St. Louis, MO, USA
Introduction:
Evidence-based interventions for eating dis-
order (ED) prevention exist, but their use beyond research
settings has been limited. To expand intervention reach, it has
been suggested that researchers involve stakeholders in pro-
gram implementation. Using delivery strategies from the evi-
dence-based implementation framework Replicating Effective
Programs, two recently launched, complementary initiatives
at Washington University in St. Louis and Stanford University
exemplify how stakeholder involvement can improve customi-
zation and deployment of a universal screening and interven-
tion initiative for EDs.
Methods:
Study researchers partnered
with leaders across university disciplines (e.g., student health
services; residential life) to solicit feedback. Meetings were
conducted prior to deployment and are ongoing.
Results:
Pre-deployment, results from stakeholder meetings yielded
3 themes: 1) changes to the screening tool and intervention
algorithm; 2) preferences regarding which clinical ED pop-
ulations to refer for treatment; and 3) strategies to improve
uptake. Suggestions were incorporated into program delivery
based on scientific and clinical merit. Post-deployment, ac-
ceptability and satisfaction ratings will be assessed at the end
of the academic year.
Conclusions:
Stakeholder involvement
enabled the successful launch of these programs, demon-
strating strategies for using an implementation framework
to scale up research-based interventions for widespread
deployment.
POSTER SESSION 2 ABSTRACTS