34
EDRS 2013
more likely to use antidepressants, antipsychotics, mood stabilizers
(
antiepileptics, lithium), anxiolythic (benzodiazepines) and hypnotic
agents. Those treated for AN and BN were more likely to use drugs
against alcohol-dependency, while those with BED were more likely to use
analgesics (opioids, paracetamol), drugs against opioid-dependency, and
highly selective agents against migraine. No difference between patients
and controls were observed in the use of psychostimulants.
Conclusions:
Patients treated ED appear to develop substance abuse problem, which
subtype differs between those with AN/BN compared to those with BED.
Individuals with BED use wide range of pain medications including
anti-migraine drugs implying increased prevalence of migraine in BED
population.
T51
A Pilot Study Using Ecological Momentary Assessement (EMA) yo
Examine Negative Affect, Loss of Control (LOC) Eating and Heart
Rate Variability (HRV) in Adolescent Girls
Lisa M Ranzenhofer
1
,
Scott Engel
2
,
Ross D Crosby
2
,
Mark Haigney
1
,
Omni
Cassidy
1
,
Anna Vannucci
1
,
Marian Tanofsky-Kraff
1
1
Uniformed Services University of the Health Sciences, Bethesda, MD,
USA,
2
Neuropsychiatric Research Institute, Fargo, ND, USA
LOC eating has been linked to self-reported stress. Yet, there are limited
data relating LOC eating to physiological stress indices including heart
rate (HR) and parasympathetic control of the heart (parasympathetic
HRV). Seventeen girls (14.8±1.6y, 24% Non-Hispanic White; BMIz
2.2
±0.4) with LOC, assessed via the EDE, completed EMA to examine
momentary negative affect and LOC eating at stratified intervals and
before and after eating. HR and HRV were recorded via ambulatory
monitoring for 2 days. Multilevel analyses revealed that mean daily
negative affect was associated with lower 24-hour parasympathetic HRV
(
p
=.04) and momentary negative affect was associated with greater
momentary HR (
p
<.01). Mean daily LOC eating was unassociated with
24-
hour HR (
ps
>.25) and parasympathetic HRV (
ps
>.26). Examination
of parasympathetic HRV trajectories during the 3 hours preceding eating
episodes revealed linear, quadratic and cubic interaction effects of time
by LOC (
ps
<.04), suggesting that parasympathetic HRV trajectories
preceding eating differ by eating episode type. In contrast to relatively
stable parasympathetic HRV trajectories preceding non-LOC episodes,
those preceding LOC eating were characterized by a decrease, followed
by an increase, in parasympathetic HRV. This autonomic pattern is
consistent with a stress response. The combination of findings that HRV is
unrelated to daily LOC, but fluctuates prior to LOC episodes, suggest that
LOC eating may serve a regulatory function.
T52
Admission BMI But Not Rate of Weight Gain Predicts Refeeding
Hypophosphatemia and Elevated Transaminases in Inpatients with
Anorexia Nervosa
Graham W. Redgrave
1
,
Janelle W. Coughlin
1
,
Colleen Schreyer
1
,
Saniha
H. Makhzoumi
2
,
Angela S. Guarda
1
1
Johns Hopkins University School of Medicine, Baltimore, MD, USA,
2
University of Maryland, Baltimore County, Baltimore, MD, USA
Purpose
:
Refeeding syndrome, marked by low phosphate, is a
potentially life-threatening complication of the treatment of anorexia
nervosa (AN) and may include elevations in the liver enzymes alanine
and aspartate aminotransferase (ALT, AST).
Methods
:
We modeled
predictors of hypophosphatemia and elevated AST and ALT in 315 AN and
subthreshold AN inpatients (382 admissions) undergoing rapid refeeding
(2
kg/wk weight gain) in a hospital-based eating disorders program. Binary
logistic regression analyses were performed, with age, race, and sex in
step 1, and rate of weight gain, admission body mass index (BMI), and
diagnosis (restricting vs. purging) in step 2.
Results
:
Hypophosphatemia
and elevated ALT and AST occurred in 18%, 38%, and 35% of the sample,
respectively. Admission BMI, but not rate of weight gain or diagnosis,
predicted all three outcomes [OR (95% CI) for hypophosphatemia=1.55
(1.33-1.80);
ALT=1.51 (1.35-1.69); AST=1.54 (1.37- 1.74)]. Age and
female sex were negative predictors of elevated AST [OR (95% CI)
for age=0.97 (0.96-0.99); sex=0.22 (0.10-0.49)].
Conclusions
:
Rapid
refeeding produces modest rates of refeeding hypophosphatemia and liver
enzyme elevation, which are predicted by admission BMI rather than by
rate of weight gain. These findings are at odds with the general refeeding
syndrome literature, suggesting that AN patients may be refed rapidly, with
less danger to metabolic and hepatic function than previously thought.
T53
Social Perception in People with Eating Disorders
Beth Renwick
1
,
Hannah DeJong
1
,
Martha Kenyon
1
,
Nelum
Samarawickrema
1
,
Rachel Loomes
2
,
Charlotte Watson
3
,
Shreena
Ghelani
3
,
Ulrike Schmidt
1
1
King’s College London, Institute of Psychiatry, Department of
Psychological Medicine, Section of Eating Disorders, London, United
Kingdom,
2
The Warneford Hospital, Cotswold House, Oxford Adult Eating
Disorder Service, London, United Kingdom,
3
Mental Health Research
Network, North London Hub, London, United Kingdom
Social perception (SP) is the ability to ascertain social cues from
behaviour in social contexts. Tied to knowledge of social rules and
social problem solving, SP is a key aspect of social cognition (SC). SP
is distinct from emotion recognition and theory of mind and is yet to be
investigated in eating disorders (ED). This study aimed to investigate SP
in anorexia nervosa (AN) and bulimia nervosa (BN) patients. Outpatients
with AN (restricting (AN-R): n=51; binge-purge (AN-BP): n=26) or BN
(
n=57) and Healthy Controls (HC) (n=50) completed the Interpersonal
Perception Task (IPT). The task includes 15 video-clips of complex social
situations relating to intimacy, status, kinship, competition and deception
.
Participants assess
relationships between protagonists’ based on non-
verbal cues. Overall, there was no difference between groups on IPT
total and subscale scores. Group differences on the intimacy subscale
approached significance so post hoc comparisons were carried out. AN-R
participants were significantly worse than HCs in determining the degree
of intimacy between others. SP is largely preserved in ED patients. Film
scenarios create the role of social observer and tap into cognitive rather
than emotional SC, making the task easier for patients. AN-R patients
were impaired in detecting intimacy in social situations; this may be due to
poor relationship experience. Further research is required to establish the
link between interpersonal difficulties and ED psychopathology.
T54
“
Do I Look Dissatisfied In This?” A Sociocultural Model of the
Relationship Between Fat Talk and Body Dissatisfaction Among
Young Women
Rachel F Rodgers
1,2
,
Bernice R Garnett
3
,
Robert Buelow
3
,
Debra L
Franko
1
,
Carolyn B Becker
4
,
S Bryn Austin
3
1
Northeastern University, Department of Counseling and Applied
Educational Psychology, Boston, MA, USA,
2
Laboratoire de Stress
Traumatique, EA- 4560, Universite Paul Sabatier, Toulouse, France,
3
Harvard School of Public Health, Department of Social and Behavioral
Sciences, Boston, MA, USA,
4
Trinity University, San Antonio, TX, USA
Purpose
:
Fat talk describes gendered body talk whereby women and
girls engage in self-disparaging conversations about their bodies. It
has been proposed that fat talk might be related to body dissatisfaction
within a sociocultural framework, however empirical data are lacking.
The aim of the study was to test a sociocultural model in young women
to investigate whether the effects of sociocultural pressure and fat-talk on
body dissatisfaction are mediated by thin-ideal internalization and social
comparison.
Methods
:
A sample of 118 female college students [mean
(
SD) age = 20 (1.3) years] completed a survey assessing sociocultural
pressure, fat talk, thin-ideal internalization, physical appearance
comparison, and body-image dissatisfaction. Factor analysis and path
analysis were conducted.
Results
:
An initial factor analysis revealed 2
dimensions of fat talk: fat talk engagement and discomfort. Only fat talk
engagement was consistently correlated with body-image variables. Path
analyses revealed that the hypothetical model was a poor fit to the data.
Examination of the modification indices showed that the addition of a
direct pathway between fat-talk and body dissatisfaction would improve
the fit. With this additional pathway, the model was a good fit, explaining
46%
of the variability in body dissatisfaction.
Conclusions
:
Fat talk may
play an important role in the development of body-image concerns and
efforts to develop interventions aiming to decrease fat talk are needed.
T55
The Sociocultural Attitudes Towards Appearance Questionnaire-4
(
SATAQ-4): Validation in College Males
Lauren M. Schaefer
1
,
Natasha L. Burke
1
,
J. Kevin Thompson
1
,
Leslie J.
Heinberg
2
,
Rachel M. Calogero
3
,
Kelly L. Klump
4
,
Allison C. Vercellone
4
,
Drew A. Anderson
5
,
Katherine Schaumburg
5
,
David A. Frederick
6
1
University of South Florida, Tampa, FL, USA,
2
Cleveland Clinic Lerner
College of Medicine of Case Western Reserve University, Cleveland,
OH, USA,
3
University of Kent, Kent, United Kingdom,
4
Michigan State
University, Lansing, MI, USA,
5
University at Albany - State University of
New York, Albany, NY, USA,
6
University of Hawaii at Manoa, Manoa, HI,
USA
Research suggests that rates of body dissatisfaction among men may
be on the rise; however, relatively few studies have examined putative
risk factors for body dissatisfaction in males. There is reason to believe
that established risk factors for women (i.e., internalization of appearance
ideals and sociocultural pressures to meet such ideals) may have
relevance in the etiology of male body dissatisfaction. The Sociocultural
Attitudes Towards Appearance Questionnaire-4 (SATAQ-4) was developed
to assess such factors in men and women and has been validated
in females. The measure consists of 22 items and five subscales:
Internalization: Muscular/Athletic, Internalization: Thin/Low Body Fat,
Pressures: Media, Pressures: Peers, and Pressures: Family. The purpose
of the current study is to validate the SATAQ-4 in males, which will allow
for examination of these risk factors in men and a comparison of risk
factors across genders. Data is being collected across 4 geographically
diverse sites in the United States. The current sample size is 230, and
data collection is ongoing. Preliminary data indicate the 5-factor structure
is similar to that for females. Internal consistency for the full scale, 2
internalization subscales, and 3 pressures subscales of the SATAQ-4 are
POSTER SESSION 1 ABSTRACTS
