Basic HTML Version
EDRS 2012
38
T52
PHYSIOLOGICAL RESPONSE TO ENERGY INTAKE IN
MALNOURISHED ADOLESCENTS WITH ANOREXIA NER-
VOSA: PRELIMINARY FINDINGS
GRAEME O’CONNOR
1
, DASHA NICHOLLS
1
, ATUL SIN-
GHAL
2
1
Great Ormond street Hospital, London, United Kingdom,
2
Institute of Child Health, London, United Kingdom
Background
Adolescents with AN are admitted to hospital
for nutritional resuscitation. Refeeding these malnourished
patients can adversely affect physiological function. The
most appropriate refeeding regimen for energy intake is
unknown. This study investigates the physiological response
to different energy intakes whilst refeeding adolescents with
AN (<75%mBMI).
Methods
The study was a randomized
controlled trial, conducted in 8 centres in the UK; adoles-
cents were randomly assigned to refeeding of 500kcal/ day
control group (European refeeding guidelines) or 1200kcal/
day treatment group (North American guidelines). Energy
intake was controlled by a meal plan which ensured similar
macronutrient consumption in both arms. Cardiovascular, bio-
chemical and anthropometric outcomes were monitored for
14 days.
Results
In 20 participants enrolled to date (mean:
age 13yrs; %mBMI 69%), post refeeding mean QTc interval
reduced by 13ms in the treatment group and increased by
8ms in the control group, a mean difference of 21ms; heart
rate increased equally in each group. Post refeeding serum
phosphate dropped in all participants in the treatment group.
Weight gain was higher in the treatment group compared with
the control group, 1.5kg and 0.7kg, respectively.
Conclu-
sion
Preliminary data suggests that the 1200kcal group was
associated with a more rapid weight gain and improved QTc
interval with a greater fall in serum phosphate. Data from this
study will help to define optimal refeeding intakes.
T53
Perfectionism in young people: Factor analysis of the
Clinical Perfectionism Questionnaire
Anne E O’Shea, Thomas J Nehmy, Tracey D Wade
Flinders University, Adelaide, Australia
The role of perfectionism in the aetiology and maintenance
of eating disorders has been widely established, however the
nature of the construct itself has evolved over the last three
decades. Analysis of the most common multidimensional
measures has distinguished two factors, one focusing on high
personal standards, and the second on evaluative concerns.
Research on the roles of these dimensions suggests that
both are associated with elevated levels of disordered eating,
with more consistent evidence relating to the latter dimension.
A uni-dimensional construct of “clinical perfectionism” focus-
sing on the mechanisms of maintenance of eating disorders,
and measured using the Clinical Perfectionism Questionnaire
(CPQ), offers a more parsimonious approach to examining
disordered eating and perfectionism. The purpose of this re-
search was to evaluate the factor structure of the CPQ in an
Australian sample of young people.
Method:
Using a sample
of 893 young people aged 25 and under, exploratory factor
analysis (principal components) was conducted followed by
confirmatory factor analysis (CFA) using AMOS.
Results:
Two factors were identified with CFA fit indices ranging from
moderate to good. The correlations of these two factors with
weight concern and negative affect, risk factors for disordered
eating, will be examined.
Conclusions:
The measurement of
perfectionism in young people and its relationship to eating
disorder risk factors will be discussed.
T54
ABERRANT REWARD PROCESSES IN ANOREXIA NER-
VOSA : LIKING VERSUS WANTING FOR HIGH AND LOW
CALORIE FOOD
Rebecca J Park
1
, Felicity A Cowdrey
1
, Graham Finlayson
2
1
Oxford, United Kingdom,
2
Leeds, United Kingdom
In the primary domain of food reward, individuals with anorex-
ia nervosa (AN) appear to spend much time preoccupied with
anticipatory wanting food, yet paradoxically seem unable to
experience normal enjoyment from the act of eating. Current
approaches for understanding food reward recognise the role
of both affective and motivational (liking and wanting) pro-
cesses in driving human eating behaviour. Few studies have
applied this framework to AN, yet dissociation between liking
and wanting may aid understanding of the complex eating
behaviours seen in AN. We have developed a novel computer
based procedure that measures implicit and explicit pro-
cesses of liking and wanting for high and low calorie foods.
Using this novel task, responses were compared across three
groups of AN participants (current AN, weight-restored AN
and fully recovered AN) as well as healthy control participants
(HCs). Current AN participants explicitly wanted high calorie
foods less than the other groups but both the current AN and
weight-restored group demonstrated less implicit wanting for
high calorie food and more implicit wanting for low calorie
food. The relative preference for high versus low calorie foods
seen in HCs, as indicated by the frequency of food choice,
was inverted in AN. The aberrant response to food that char-
acterises AN may be driven by altered motivational wanting
rather than hedonic liking, independent of weight status.
Clinical and research implications are discussed.
T55
AN EVERYDAY LANGUAGE MEASURE OF EATING DIS-
ORDER RISK FOR YOUTH
Carolyn M Pearson
1
, Leila Guller
1
, Laura MacPherson
2
, Carl
W Lejuez
2
, Gregory T Smith
1
1
University of Kentucky, Lexington, KY, USA,
2
University of
Maryland, College Park, MD, USA
Introduction.
Eating disorder assessment measures typically
assess symptoms, such as frequency of binge eating and
compensatory behavior. Symptom measures are of obvious
importance, but there is also a need to assess risk among
adolescents, in the absence of diagnosable symptoms. We
tested a risk measure that uses everyday language familiar
to adolescents that was originally developed for use with
college students; the measure is called the COEDS. Items
are pre-symptomatic, e.g., “I feel very competitive with other
girls/boys who have better bodies than I do.” We evaluated
the reliability, stability, and longitudinal predictive validity of
the COEDS in a sample of early adolescents.
Method.
We
administered the COEDS and assessed BMI, pubertal status,
and restricting behavior in a sample of 246, first when they
were 13 years old and again one year later.
Results.
Reten-
tion in the study was 93%. The COEDS was internally consis-
tent both years (α = .85 and .87) and stable over one year (r
= .73). Girls scored higher than boys. In multiple regression,
year 1 restricting (b=.29), year 1 BMI (b=.23), and, beyond
those two effects, year 1 COEDS scores (b=.24) predicted
increased restricting across the one year period.
Conclusions.
The COEDS, which assesses pre-symptomatic concerns in
everyday language familiar to adolescents, proved to be reli-
able, stable, and predictive of increased restricting behavior
one year later in a sample of early adolescents. It may thus
prove useful.
T56
NORMS AND RELIABILITY OF THE EATING DISORDER
EXAMINATION QUESTIONNAIRE (EDE-Q) AMONG HIGH
SCHOOL AND UNIVERSITY MEN
Deborah L Reas, Maria N Øverås, Øyvind Rø
Oslo University Hospital, Regional Eating Disorders Ser-
vice (RASP), Division of Mental Health and Addiction, Oslo,
Norway
Introduction:
The EDE-Q is a widely used measure world-
wide, yet data on men remains scarce. Similar to other
ED instruments, it was originally developed for adolescent
females and the extent to which it addresses male shape and
weight concerns is important to ascertain. This study aimed
to establish normative and reliability data for the EDE-Q in
a sample of young men.
Methods:
A community sample of
250 men aged 15 to 30 years (mean = 19.7; SD = 2.3) with
an average BMI of 23.1(3.1) were recruited from high school
and university settings.
Results:
Mean global EDE-Q was
0.44 (0.52), with subscale means ranging from 0.15 (0.38) for
POSTER SESSION 1 ABSTRACTS